Website Privacy Statement
Mission Pharmacal Company is aware of the importance of protecting the privacy of visitors to our websites. Personally identifiable information, such as name, addresses, telephone numbers, and visitor comments voluntarily submitted to Mission Pharmacal Company will not be utilized for marketing purposes without obtaining visitor authorization prior to the submission of information. Mission Pharmacal Company reserves the right to utilize internally, for operations purposes, any information provided by visitors to this website.
This website may track IP addresses, and may utilize "session cookies" to collect information about visitor activities on this website.
Mission Pharmacal Company has no duty or obligation to respond to emails sent to the Webmaster of this website and cannot assure the confidentiality of such communications.
Mission Pharmacal Company websites may contain links to other websites that may contain useful information. Mission Pharmacal Company's privacy policies do not apply to those websites that are not owned and operated by Mission Pharmacal Company. Please contact those other websites for information pertaining to their privacy policies.
Mission Pharmacal Company reserves the right to revise this Website Privacy Statement, as necessary.
Medical Disclaimer
If you have a medical emergency, call 911 immediately.
The contents of this website are provided for informational purposes only. The website cannot replace your healthcare provider's medical advice, diagnosis, or treatment. Only a qualified health provider can properly address specific questions regarding your health or nutritional needs. Nothing on this website should be used to replace your healthcare provider's advice. Use of any information provided by this website is done at your own risk.
Compliance Statement
Mission Pharmacal Company has implemented Compliance Programs that include, among other provisions, a code of ethical conduct for interactions with healthcare professionals, and policies to safeguard the privacy and security of patient healthcare information.
For more information on these Compliance Programs, contact Mission Pharmacal Company's Compliance Officer at our toll-free telephone number: (800) 531-3333.
Terms of Use
Through your access to and use of this website, you accept, without limitation or qualification, the terms and conditions as set forth below.
If you do not wish to accept and be bound by the following terms and conditions, you may not use this website or the information contained herein.
Mission Pharmacal Company offers services and products to prevent, diagnose, and treat diseases and improve health. The prescription medications manufactured by Mission Pharmacal Company are regulated by government agencies in each of the countries in which it does business. Some of these regulations restrict the publishing of prescribing information on this website. You must speak with your qualified health care provider regarding any questions you may have regarding prescription medications and do not rely on the content of this website for such information. Nothing contained in this website is, nor shall it be construed as, medical diagnosis, treatment, or advice. Nothing contained in this website may take the place or substitute for, or augment, consultations and/or advice from physicians or other competent health care professionals or providers. See your physician or other health care provider.
Mission Pharmacal Company has developed this website as a service to consumers. However, some of the information on this website will become outdated, making it incorrect, and will only be updated periodically, if at all. As such, Mission Pharmacal Company shall not accept liability for consumer reliance on incorrect or outdated information on this website. Mission Pharmacal Company further assumes no liability or responsibility for any errors or omissions in any of the content of this website or the information contained therein.
None of the information on this website is medical advice. Consult your health care provider with questions regarding any medication or nutritional supplement. You must read the labels and inserts and follow directions on all products manufactured and/or marketed by Mission Pharmacal Company. Mission Pharmacal Company shall not be responsible for alleged damages incurred by consumers who rely on the information on this website as medical advice. By viewing this website, it is agreed that Mission Pharmacal Company shall not be liable for any direct, indirect, consequential, incidental, exemplary, or punitive damages arising out of your access to or use of this website or its contents. Additionally and separately from the above, the information provided on this website is provided "AS IS" WITHOUT ANY WARRANTIES OF ANY KIND, EITHER IMPLIED OR EXPRESSED, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF FITNESS FOR A PARTICULAR PURPOSE, NON-INFRINGEMENT, AND MERCHANTABILITY. The exclusion of implied warranties may not be enforceable in your particular jurisdiction. Further, Mission Pharmacal Company does not assume responsibility for any damages to your computer equipment which may result from accessing and/or using this website including, without limitations, that caused by computer viruses.
This website and its contents are designed to comply with United States laws and regulations. While this website and its contents may be accessible in other jurisdictions, this website and its contents are intended for access and use in the United States only.
Mission Pharmacal Company cannot control, and as such cannot take responsibility for, information found on websites posted by third parties. Any links on this website to a third-party's website is for your convenience only, and is not an endorsement of the content of the third-party's website.
Copyright and Intellectual Property
All content of this website is owned by Mission Pharmacal Company and is protected by worldwide copyright laws. The trademarks, service marks, trade names, trade dress, and products featured on this website are protected by the laws of the United States and those of other countries and jurisdictions around the world.
You may print or copy materials published by Mission Pharmacal Company on this website for personal, non-commercial use only. You may not copy, reproduce, distribute, display, or otherwise use any materials published on this website for public or commercial purposes without the prior express written consent of Mission Pharmacal Company. Materials copied from this website for personal use or with prior written consent of Mission Pharmacal Company must, in any event, retain all copyright and other proprietary notices and disclaimers appearing in connection with such materials on this website.
Images of people or places appearing on this website are either the property of Mission Pharmacal Company or used with permission. Any use of the images of such people or places by you is strictly prohibited, and may constitute infringement or violation of communications, copyright, trademark, privacy and/or publicity laws.
Nothing contained on this website shall be construed as conferring by estoppel, implication, or otherwise any license or right under any trademark, copyright, or patent of Mission Pharmacal Company or any third party. Mission Pharmacal Company vigorously enforces its intellectual property rights to the fullest extent of the law.
User Representations
You represent that you are at least 18 years of age and that you have read, understood, and agreed to the foregoing. You represent that you have the legal right and capacity to accept the foregoing terms and conditions and be bound by them. You represent that you will use this website and the information contained therein in accordance with the foregoing terms and conditions.
Indemnification by User
YOU AGREE TO INDEMNIFY, DEFEND, AND HOLD HARMLESS MISSION PHARMACAL COMPANY, ITS OFFICERS, DIRECTORS, EMPLOYEES, AND AGENTS FROM ANY AND ALL DAMAGES, LOSSES, COSTS AND EXPENSES, INCLUDING REASONABLE ATTORNEYS FEES, RESULTING FROM ANY VIOLATION OF THESE TERMS AND CONDITIONS BY YOU.
Waiver and Release of Liability by User
YOU AGREE THAT NEITHER MISSION PHARMACAL COMPANY, ITS OFFICERS, DIRECTORS, EMPLOYEES, OR AGENTS SHALL HAVE ANY LIABILITY TO YOU UNDER ANY THEORY OF LIABILITY INCLUDING, WITHOUT LIMITATION, NEGLIGENCE OR GROSS NEGLIGENCE, OR INDEMNIFICATION, IN CONNECTION WITH YOUR USE OF THIS SITE AND/OR THE CONTENTS AND/OR INFORMATION HEREIN. YOU HEREBY RELEASE AND FOREVER WAIVE ANY AND ALL CLAIMS YOU MAY HAVE AGAINST MISSION PHARMACAL COMPANY, ITS OFFICERS, DIRECTORS, EMPLOYEES, AND/OR AGENTS BASED UPON OR RELATED TO SUCH USE.
Governing Law and Exclusive Venue
You agree that any dispute arising from or related to your access to or use of this website, and/or the content or information contained herein, and/or the foregoing terms and conditions, shall be governed by Texas law. You agree that exclusive venue for any dispute arising from or related to your access to or use of this website, and/or the content or information contained herein, and/or the foregoing terms or conditions, shall be exclusively in a court of competent jurisdiction in Bexar County, Texas, and you hereby agree to submit to personal jurisdiction and exclusive venue in such court of competent jurisdiction in Bexar County, Texas.
Terms and Conditions Subject to Revision
The foregoing terms and conditions are subject to revision and/or modification by Mission Pharmacal Company at anytime. Such revisions or modifications are effective immediately upon posting, publishing, or otherwise notifying you of the same. You are bound immediately by any such modifications or revisions, and consequently you should visit this page periodically to review these terms and conditions and to check for modifications or revisions.
Thiola® is a prescription drug that helps prevent cystine (kidney) stones from forming in patients who are resistant to treatment with a modified diet and high fluid intake, or patients who have adverse reactions to the drug d-penicillamine.
Important Safety Information
Thiola® is not for everyone. Its safety and effectiveness have not been established for patients under the age of 9, and there are no adequate and well-controlled studies in pregnant women.
Do not take Thiola® if you are pregnant or may become pregnant, unless your doctor has discussed the risks with you and determined that the prevention of stones outweighs possible risks to the fetus. If you are nursing, Thiola® may pass through your breast milk and lead to potentially serious side effects for your infant, so you should not breastfeed while taking Thiola®.
High doses of Thiola® in laboratory animals have been shown to interfere with pregnancy and survival of the fetus. Additionally, d-penicillamine has been shown to cause birth defects in animals at very high doses, so although these results were not found with Thiola®, a similar outcome is possible. No long-term animal studies have been done to examine the cancer-causing potential of Thiola®, so you should discuss the risks with your doctor and only take Thiola® if it is necessary.
Do not take Thiola® if you have a history of blood disorders such as aplastic anemia (a condition in which the body does not produce enough new blood cells), agranulocytosis (a disorder characterized by a drop in white blood cells called granulocytes), or thrombocytopenia (an abnormal decrease in the number of platelets).
If you take Thiola®, your doctor may conduct a variety of blood and urine tests to check for possible complications and perform annual abdominal scans to monitor the size and appearance of stones.
Some patients may develop a drug-induced fever while taking Thiola®, usually during the first month of treatment. If this occurs, talk with your doctor and discontinue use until the fever subsides. Your doctor may instruct you to begin taking a small dose, and then increase it gradually until you reach the appropriate dosage.
You may notice a reduced sense of taste while taking Thiola®. Some patients also experience wrinkling or fragile skin after long-term treatment.
Other side effects of Thiola® may include a generalized rash accompanied by itching, which typically occur during the first few months of treatment. Antihistamines can help reduce the itching, and the rash will normally disappear once you stop taking Thiola®. Less often, patients who take Thiola® for more than 6 months may develop a rash late in the course of treatment. This rash is usually located on the upper body and associated with intense itching. It typically goes away slowly after discontinuing treatment and returns after re-starting treatment.
No deaths have been reported as a result of Thiola® treatment; however, a fatal outcome has been reported with certain complications of d-penicillamine therapy, including reduced white blood cells, red blood cells, or platelets; Goodpasture's syndrome (an autoimmune disorder that affects the lungs and kidneys); and myasthenia gravis (an autoimmune disorder characterized by muscle weakness). Do not take Thiola® if you have a history of these conditions.
Seek immediate medical attention and discontinue use if you notice symptoms such as fever, sore throat, chills, bleeding, easy bruisability, coughing up blood, muscle weakness, blistering or raw areas on the skin or mucous membranes, joint pain, swelling of the lymph nodes, or swelling in your legs, as these may be signs of a serious reaction to the drug.
Although Thiola® is reportedly less toxic than d-penicillamine, it could potentially cause all the side effects reported for d-penicillamine. Additional side effects might include a reduced sense of smell, throat inflammation, nausea, vomiting, diarrhea or soft stools, loss of appetite, abdominal pain, bloating, gas, oral ulcers, hives, warts, swelling of the throat, difficulty breathing, respiratory distress, fatigue, muscle pain, swelling or fluid build-up in the lungs, and blood or high amounts of protein in urine. These reactions are more likely to develop during Thiola® therapy among patients who had previous reactions to d-penicillamine. Talk to your doctor about any unusual side effects.
Jaundice and abnormal liver function tests were reported during Thiola® treatment for conditions unrelated to cystine stones, however, these results were not directly linked to Thiola®.
To report negative side effects, contact Mission Pharmacal Company at 1-800-298-1087 or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Urocit® -K (potassium citrate)
Inhibits formation of both calcium oxalate and uric acid stones
Website»
Thiola® (tiopronin)
For the prevention of cystine kidney stone formation
Website»
Lithostat® (acetohydroxamic acid)
Adjunctive therapy in patients with chronic urea-splitting urinary infection
Website»
StoneDisease.org
Information about the causes, symptoms, diagnosis, and treatment of stone disease Website»
